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I've been on a long list of medications for depression for many years, some worked for awhile, some not at all. Reached my lowest point 6 months ago and haven't really recovered. I finally took matters into my own hands and asked the doctor for Wellbutrin as the ratings looked overall pretty good. On day 3 now and seem to feel uplifted already.... Actually making plans for the day which I haven't done in months...still apprehensive to give a 10 rating but keeping hope. Had trouble sleeping but no other side effects have shown up yet.



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The FDA considers the generic form of bupropion XL 300 mg (Teva Pharmaceuticals) bioequivalent and therapeutically equivalent to (interchangeable with) Wellbutrin XL 300 mg.

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Research indicates that increased levels of these two neurotransmitters has a positive effect on depression and anxiety, reports the Mayo Clinic.

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You should not take more than your prescribed dose and doing so may increase your risk of having a seizure.

The Wellbutrin is not approved for use for anxiety and this may be why you are still experiencing high anxiety.

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When I tried the XR version of wellbutrin it also did not work for me.

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Wellbutrin XL (bupropion hydrochloride extended-release) is an antidepressant used to treat major depressive disorder and seasonal affective disorder.

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WELLBUTRIN XL should be swallowed whole and not crushed, divided, or chewed.

Spina E, Scordo MG, Arrigo C. Metabolic drug interactions with new psychotropic agents. Fundam Clin Pharmacol.

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Some doctors prescribe it as an “add on” drug to enhance the effects of an antidepressant like Zoloft, for example, or because Wellbutrin can counteract the unwanted sexual side effects of certain antidepressants.

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Remember, for Wellbutrin patient assistance or answers to any questions you may have, you should talk to your doctor or pharmacist.

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I'm considering going back on Wellbutrin like I did 7 years ago.

Research increasingly indicates that bipolar disorder may also share genetic factors with other disorders such as schizophrenia, epilepsy.

Armour Thyroid for Hypothyroidism but have been on Wellburtrin for the last 6 years and tried to quit cold turkey thinking that it could interfere with this thyroid med.

My experience is that when I was concerned about the interaction of dyes used with CT and MRI scans with WB, my Dr said skipping the night and next morning dose would not hurt my depression and would have it out of my system enough so that is would not cause a problem with the dyes.

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Bupropion passes into breast milk and could be harmful to a nursing baby.

In clinical trials with bupropion HCl immediate-release, 10% of patients and volunteers discontinued due to an adverse reaction.

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Celexa then went to Zoloft, and Zoloft worked for a bit but once things began to get difficult again I had to switch to another one, which was Wellburtin.

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