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I started taking this medication last night, Feb 19 2012 , and I have experienced a lot of gas. I was up most of the night going to bathroom, and today I'm experiencing a strange sensation in my chest but its not pain. It almost feels like a tingle and I have a cough also. I also have anxiety and headaches.
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I have chronic angina and for me the ideal medication is Ranolazine. The diagnosis was a shock for me in spite of the fact that I didn't have any bothering symptoms, slight tightness in my chest from time to time, difficuly when breathing, but I thought that was due to recent cold. However the doctor explained me that there were problems with my heart and it didn't get enough oxygen with the blood. Therefore I had to take certain medications to support my arteries and their functions. With Ranolazine my symptoms are easy to control I can prevent another attack of chest pain and live as if there is no angina. But when it is cold outside or too humid I can not breathe normally and afterwards still get some pain in the chest. But I am alive and I have no critical condition and I am grateful to Ranolazine for these facts. What is also very important for me is that I can sleep well at night without waking up suffocating. Recommend it to other angina victims.

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No proarrhythmic effects observed in 7-day Holter monitor recordings in patients with acute coronary syndrome receiving ranolazine.

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Beta blockers are recommended as first-line therapy for the management of stable angina in all patients with established CAD.

Unlike other agents, however, ranolazine does not have significant adverse effects on heart rate or blood pressure, although it has been associated with prolongation of the QT interval, raising questions about its safety, the authors noted.

A generic drug is actually its brand-name equivalent, although it doesnt bear the original trademark and looks slightly different.

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However, a month or so after I started taking the medicine, I started having "shaking episodes".

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Calcium channel inhibitors have potent anti-ischaemic effects, but have had no impact on long-term outcome, either alone or in combination with beta-blockers.

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The 17 folks were followed for years, and in all except one, the relief from the painful neuropathy continued, or improved even further.

Patients with diabetes mellitus have more diffuse atherosclerotic disease and are prone to a higher anginal burden compared to their non-diabetic counterparts.

She was discharged home, and ranolazine was resumed as part of her discharge medication list.

Heparin administration requires careful monitoring for bleeding, and when the drug is stopped, the patient must be watched for “rebound” ischemic episodes that sometimes occur during the subsequent 24 hours.

Anti-anginal efficacy of ranolazine when added to maximal therapy with conventional therapy: The efficacy of ranolazine in chronic angina trial.

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Effect of two intensive statin regimens on progression of coronary disease.

Analyses of exercise data from patients taking calcium antagonists compared with those not receiving calcium antagonists produced similar findings.

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CARISA was a study in 823 chronic angina patients randomized to receive 12 weeks of treatment with twice-daily Ranexa 750 mg, 1000 mg, or placebo who also continued on daily doses of atenolol 50 mg, amlodipine 5 mg, or diltiazem CD 180 mg.

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Mortality rates attributable to cardiovascular disease have declined in recent decades, but the burden of disease remains high.

Although many non-invasive cardiac investigations can be used to support the diagnosis of SCAD, the optimal use of resources is only achieved if pre-test probabilities, based on simple clinical findings, are first taken into consideration.

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In general, the elevation has a rapid onset, shows no signs of progression during long-term therapy, is reversible after discontinuation of Ranexa, and is not accompanied by changes in BUN.

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