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I have diabetes type 2 for more than 10 years out of my 29 years of life. During this time I have tried out many medications doing my best not to get insulin dependent. Actually in spite of all the wide range of diabetes treatment medication on the market today, controlling your blood sugar levels can be quite a difficult task as the majority of meds have unexpected side effects, others produce not enough effect on glucose in your blood. Last year I started on Precose and I find this medication to be one of the best solutions available now. With Precose controlling my blood sugar is much easier and in general my life is more under my control. I can eat more differentiated food, lead more active life and at the same time rest assured my health is out of danger at the level it could be. My doctor is also very satisfied with the results Precose provides and his prognoses are more than just optimistic.
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I am a 50-year-old female and I have diabetes type 2 for more than 25 years. In my life the disease has created hundreds of problems for me and dangerous situations, but I still remain independent from insulin and this is a positive aspect. May be I was lucky to get medications that with higher or lower effectiveness helped me control the sugar in my blood and allowed me to stay away from most horrible side effects and complications. I do have problems with extra weight but I do my best to reduce it and I consider myself to be quite successful at it. I am on Precose now, I take it three times a day at the beginning of my meal. It is not difficult to take it. At first when I started Precose I had minor problems with gas, but then the side effect disappeared and now I am absolutely happy with the medication. Besides, I enjoy the way I can order Precose online and have it delivered for free right to my place. It is very convenient and even cheaper that buying the medication in the local drugstore.
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The plasma elimination half-life of Acarbose activity is approximately 2 hours in healthy volunteers.
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Dosing and Time to Take EffectYou should start out taking the lowest dose of Acarbose available and then work up.
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Monitor digoxin; and for hypoglycemia if used with insulin or a sulfonylurea.
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Four additional secondary outcomes were defined for the specific evaluation of cardiac or infectious events: death from cardiac causes, death from infectious causes, the composite of the first hospitalization for cardiac causes or death from cardiac causes, and the composite of the first hospitalization for infectious causes or death from infectious causes.
Initiation with once-daily biasp 30 results in superior outcome compared to insulin glargine in Asians with type 2 diabetes inadequately controlled by oral anti-diabetic drugs.
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Next time, do I leave my pump on for the tests and, what are your overall impressions about the possibility of LADA given the low insulin needs and the quickness of becoming insulin dependent.
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Another positive attribute of bromocriptine is its favorable effects on weight.
In systemic circulation (beyond the liver) cinnamon also possesses anti-diabetic effects.
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In the Diabetes Prevention Program (DPP) trial, diet and exercise alone decreased the rate of onset of diabetes mellitus by 58% after 3 years.
Because of this, the insulin is not able to lower your blood sugar properly and you will have too much sugar in your blood.
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It's not branded the way the newer analog insulins are.
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Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995.
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Acarbose tablets were studied as monotherapy and as combination therapy to sulfonylurea, metformin, or insulin treatment.
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Pramlintide helps slow the absorption of glucose by decreasing the speed at which food leaves your stomach.
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The maximum dose of gliclazide (regular formulation) between studies varied from 240 to 320 mg.
As a different option, acarbose can also be started at acarbose 25 mg once daily, slowly increasing up to three times daily (this can help to decrease stomach side effects).
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In the 59 cases where follow-up was recorded, hepatic abnormalities improved or resolved upon discontinuation of Acarbose tablets in 55 and were unchanged in two.
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This change was shown to correlate to an activity increase for liver glycogen phosphorylase.
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The insulin treatment for type 1 diabetes is available in several forms including long-acting, short-acting and rapid-acting therapies.
Drink plenty of fluids while taking this medication unless your doctor tells you otherwise.
When the number of people who developed diabetes during the three month "washout" phase during which the drug was discontinued was included in the study results, a further 15.
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It may deplete Vitamin B-12 because it may alter the ability of the body to absorb vitamin B-12 from the gut.
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During follow-up, 392 patients left their dialysis center for reasons other than death, including 194 who received a transplant (95 in the standard-dose group and 99 in the high-dose group; 93 in the low-flux group and 101 in the high-flux group) and 198 others who switched methods of dialysis or transferred to nonparticipating facilities.
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Meier JJ, Baller B, Menge BA, Gallwitz B, Schmidt WE, Nauck MA: Excess glycaemic excursions after an oral glucose tolerance test compared with a mixed meal challenge and self-measured home glucose profiles: is the OGTT a valid predictor of postprandial hyperglycaemia and vice versa?
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ULN, and greater than 3 times the ULN occurred in 14%, 6%, and 3%, respectively, of acarbose-treated patients as compared to 7%, 2%, and 1%, respectively, of placebo-treated patients.
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Ask your health care provider if acarbose may interact with other medicines that you take.
ACE Consensus Panel on type-2 diabetes mellitus moves sulfonylureas to a lower priority in dual-combination or triple-combination drug selection because of the potential for hypoglycemia, weight gain, and inability to maintain glycemic control after approximately 1 to 2 years in most patients.
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EXamination of cArdiovascular outcoMes with alogliptIN versus standard of carE in patients with type 2 diabetes mellitus and acute coronary syndrome (EXAMINE): a cardiovascular safety study of the dipeptidyl peptidase 4 inhibitor alogliptin in patients with type 2 diabetes with acute coronary syndrome.
Eye exam: Diabetics should have their eyes checked by an ophthalmologist (eye specialist) each year for retinopathy, glaucoma and cataracts.
Acarbose is approved for treatment of IGT in 25 countries.
Adverse reactions include weight gain and hypoglycemia.
Acarbose does not produce hypoglycemia; however, hypoglycemia may develop if used together with sulfonylureas or insulin.
Generic brands are designed to be substitutes for more expensive brand-name goods.
Cystic fibrous, or CF, uses pancreatic enzymes to treat insufficiency with breaking down carbohydrates of the diet.
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New and emerging regulators of intestinal lipoprotein secretion.
In a one-year safety study, during which patients kept diaries of gastrointestinal symptoms, abdominal pain and diarrhea tended to return to pretreatment levels over time, and the frequency and intensity of flatulence tended to abate with time.
Acarbose has been safely used in elderly patients.
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This material is not intended to be, and should not be considered, a substitute for medical or other expert opinion.
Inhaled insulin claimed to have similar efficacy to injected insulin, both in terms of controlling glucose levels and blood half-life.
In view of its usually acceptable level of side effects that are, if they occur, mostly limited to transient gastrointestinal symptoms, acarbose could well be a strong future player in CV disease secondary prevention.
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In our analysis, Southeast Asians showed a better response to acarbose throughout the baseline HbA 1c range.
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All this has already been accomplished by the original manufacturer, and was subsequently reflected in the brand-name drug price.
There are a couple of other tests he did that haven't come back yet.
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Some cardiovascular drugs have also shown potential antidiabetes effects.
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Research is ongoing to determine the mechanisms by which acarbose provides cardiovascular benefits, but it seems clear that the benefits can be attributed, at least in part, to the fact that acarbose directly targets postprandial hyperglycaemia, which limits endothelial damage and reduces the risk of macrovascular complications.
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Additional medications may also be required to treat conditions such as hypertension or dyslipidemia.
Other inclusion criteria such as metabolic parameters or concomitant antidiabetic medication varied according to the primary objective of the different studies.
Current discouraging results from many trials of antidiabetic medications to significantly lower CV event rates in diabetic patients, should only draw further attention on alternative glucose lowering agents, among which acarbose is indeed promising.
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By Anita Baxas, Binningen, Switzerland A 53-year old male patient presented himself with non-insulin-dependent diabetes mellitus since 5 years as well as an active hepatitis C infection of unknown cause and duration.
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Yang W, Liu J, Shan Z, Tian H, Zhou Z, Ji Q, Weng J, Jia W, Lu J, Xu Y, Yang Z, Chen W: Acarbose compared with metformin as initial therapy in patients with newly diagnosed type 2 diabetes: an open-label, non-inferiority randomised trial.
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They are most commonly mild-to-moderate gastrointestinal effects, such as flatulence, diarrhea, or abdominal discomfort, and generally diminish in frequency and intensity with time.
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The most common dialyzers with low flux were the Fresenius F8 (used in 46 percent of sessions) and the Baxter CA210 (used in 43 percent); the most common dialyzers with high flux were the Fresenius F80 (used in 43 percent of sessions) and the Baxter CT190 (used in 48 percent).
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In addition, women with gestational diabetes must utilize diet or insulin therapy to control the disease, since all oral diabetes medications are contraindicated during pregnancy.
Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems.
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Hoefsloot L; M Hoogeveen-Westerveld; A J Reuser; B A Oostra (1 December 1990).
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Kato T, Inoue T, Node K: Postprandial endothelial dysfunction in subjects with new-onset type 2 diabetes: an acarbose and nateglinide comparative study.
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The risk of cardiovascular disease is two to four times as high in people with diabetes as in people without diabetes.